After you get the initial setup out of the way and have your site up and running, you'll want to monitor usage and tweak certain values so that you can get the most out of the server.
Once you feel satisfied with how the site is running after like 2-4 weeks, you'd mainly be keeping the server updated with the latest software updates as well as monitoring the logs to ensure everything works as it should.
It's not that hard and it will be a good learning experience for you, since you're inexperienced. DigitalOcean's community has an INSANE amount of tutorials and guides you can use to get started and maintain your server.
Cheers.